We have developed an algorithm to analyze secretoryvesicle distribution and docking in electron micrographs.
2
Taking together, the algorithm facilitates and expands the unbiased and efficient analysis of secretoryvesicle distribution and docking.
3
The analysis of secretoryvesicle distribution is usually performed manually, which is labour-intensive and subject to human bias and error.
4
At present, the role of Mts and kinesin in secretoryvesicle transport in exocrine epithelial cells has not been defined.
5
Our results suggest that the molecular mechanism by which PTP-MEG2 promotes secretoryvesicle fusion involves the local release of NSF from a tyrosine-phosphorylated, inactive state.
Uso de secretory vesicles em inglês
1
Neurons secrete many diffusible signals from synaptic and other secretoryvesicles.
2
However, in plant cells, there are obviously additional endosomal source compartments for secretoryvesicles.
3
It might be expected that the secretoryvesicles in different cell types use similar molecular machinery.
4
The algorithm was highly accurate in recognizing secretoryvesicles and calculating their distribution including vesicle-docking analysis.
5
Ciliated cells also are involved in the shedding of exosomes and secretoryvesicles in the lumen.
6
The exocyst is a multisubunit complex required for vectorial targeting of a subset of secretoryvesicles.
7
Unicellular root hairs elongate via localized tip growth, a process mediated by polar exocytosis of secretoryvesicles.
8
Quantal release of the principal excitatory neurotransmitter glutamate requires a mechanism for its transport into secretoryvesicles.
9
Several types of cells store proteins in secretoryvesicles from which they are released by an appropriate stimulus.
10
We found that the secreted vesicular stomatitis virus G proteins were not transported to the regulated secretoryvesicles.
11
On the other hand, only the ectopically located Sec3p subunit is capable of recruiting secretoryvesicles to mitochondria.
12
The exocyst complex was believed to target and tether post-Golgi secretoryvesicles to the plasma membrane during exocytosis.
13
Following cleavage, the BRI2-derived carboxyl-terminal peptides are transported via a regulated secretory pathway into secretoryvesicles in neuronal cells.
14
Neuroendocrine cells like chromaffin cells and PC-12 cells are established models for transport, docking and secretion of secretoryvesicles.
15
Here we found that most secretoryvesicles are delivered by myosin-V on linear actin cables in fission yeast cytokinesis.
16
Neuroendocrine secretoryvesicles discharge their cargo in response to a stimulus, but the nature of this event is poorly understood.